This is educational information, not medical advice, and The Peptide University does not sell peptides, supplies, or supplements. Many compounds discussed here are sold as “research chemicals” and are not approved for human use outside of clinical trials. Laws vary by country, and nothing here is a recommendation to obtain or use anything. Talk to a qualified clinician about your own situation.
AOD-9604 is a synthetic fragment of the C-terminus of human growth hormone. It's promoted for fat loss and is unapproved; drug development was terminated after trials.
How it works
It's theorized to stimulate fat breakdown (lipolysis) and inhibit fat storage without raising IGF-1 the way full growth hormone does. That selectivity is the marketing pitch.
The evidence
Animal studies show lipolytic effects, and a safety database of 900+ participants describes it as well tolerated — but it failed to hit statistical significance in its largest Phase IIb trial, and development was stopped in 2007. So it's well-tolerated but not shown to work well in humans.
Safety
Reported as well tolerated in trials, but with the major caveat that it wasn't shown to be effective. As with any research chemical, purity and identity of what's sold online is a separate question — see reading a COA.
FAQ
QDoes it 'burn fat without side effects'?
Marketing overstates it. Trials found it well tolerated but not clearly effective for meaningful fat loss.
QIs it approved?
No — development was terminated; it's sold as a research chemical.
Sources
This profile summarizes the following. Follow the links to read the originals — and remember that summaries age, so check for newer information.
- Emerging anabolic/regenerative peptides: mechanisms & evidence review
- AOD-9604 fat-loss peptide: mechanism & risks (Swolverine)
Inclusion here is not endorsement of any source's claims; several are cited so you can compare how different outlets characterize the same evidence.
Questions & comments
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